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Risk Factors for Delayed Elimination of Methotrexate in Children, Adolescents and Young Adults With Osteosarcoma

Background/Aim: High-dose methotrexate (HD-MTX) is pivotal chemotherapy in the treatment of patients with osteosarcoma. Blood concentrations of MTX are associated with several side effects, but there are large individual differences in the elimination of MTX. The aim of this study was to explore ris...

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Detalhes bibliográficos
Publicado no:In Vivo
Main Authors: MISAKA, KO, SUGA, YUKIO, STAUB, YUKIKO, TSUBATA, ATSUMI, SHIMADA, TSUTOMU, SAI, YOSHIMICHI, MATSUSHITA, RYO
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811654/
https://ncbi.nlm.nih.gov/pubmed/33144454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.12185
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