טוען...
Correlation Between the Metabolic Conversion of a Capecitabine Metabolite, 5’-Deoxy-5-fluorocytidine, and Creatinine Clearance
Aim: Capecitabine is a prodrug that is metabolized to its active form, 5-fluorouracil (5-FU), in three enzymatic steps. This prospective pharmacokinetic study evaluated cytidine deaminase (CDA) activity, the second drug-metabolizing enzyme that generates 5’-deoxy-5-fluorouridine (5’-DFUR) from 5’-de...
שמור ב:
| הוצא לאור ב: | In Vivo |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
International Institute of Anticancer Research
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7811603/ https://ncbi.nlm.nih.gov/pubmed/33144465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.12196 |
| תגים: |
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