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Proteolytic Processing of CD44 and Its Implications in Cancer

CD44 is a transmembrane glycoprotein expressed in several healthy and tumor tissues. Modifications in its structure contribute differently to the activity of this molecule. One modification that has provoked interest is the consecutive cleavage of the CD44 extracellular ectodomain by enzymes that be...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Int
Autori principali: Medrano-González, Priscila Anhel, Rivera-Ramírez, Osmar, Montaño, Luis Felipe, Rendón-Huerta, Erika P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811561/
https://ncbi.nlm.nih.gov/pubmed/33505471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6667735
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