Diverse Signaling by TGFβ Isoforms in Response to Focal Injury is Associated with Either Retinal Regeneration or Reactive Gliosis

Müller cells may have stem cell-like capability as they regenerate photoreceptor loss upon injury in some vertebrates, but not in mammals. Indeed, mammalian Müller cells undergo major cellular and molecular changes summarized as reactive gliosis. Transforming growth factor beta (TGFβ) isoforms are m...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Neurobiol
Hauptverfasser: Conedera, Federica Maria, Quintela Pousa, Ana Maria, Presby, David Mikal, Mercader, Nadia, Enzmann, Volker, Tschopp, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811507/
https://ncbi.nlm.nih.gov/pubmed/32219603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-020-00830-5
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