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miR-21 Induces Chemoresistance in Ovarian Cancer Cells via Mediating the Expression and Interaction of CD44v6 and P-gp

BACKGROUND: Ovarian cancer (OC), a representative female reproductive system tumor, is one of the most malignant tumors in female. The most important reason for its poor prognosis is because of its high rate of chemotherapy resistance. RESULTS: This study aims to explore the effects of miR-21 on the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Wang, Yanqing, Chen, Gantao, Dai, Fangfang, Zhang, Li, Yuan, Mengqin, Yang, Dongyong, Liu, Shiyi, Cheng, Yanxiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811474/
https://ncbi.nlm.nih.gov/pubmed/33469309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S286639
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