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X-Ray Crystallography Reveals Parallel and Antiparallel β-Sheet Dimers of a β-Hairpin Derived from Aβ(16–36) that Assemble to Form Different Tetramers
High-resolution structures of oligomers formed by the β-amyloid peptide, Aβ, are important for understanding the molecular basis of Alzheimer’s disease. Dimers of Aβ are linked to the pathogenesis and progression of Alzheimer’s disease, and tetramers of Aβ are neurotoxic. This paper reports the X-ra...
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| Yayımlandı: | ACS Chem Neurosci |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7811405/ https://ncbi.nlm.nih.gov/pubmed/32584538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00290 |
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