CNTN-1 promotes docetaxel resistance and epithelial-to-mesenchymal transition via the PI3K/Akt signaling pathway in prostate cancer

INTRODUCTION: Therapy options for prostate cancer (PCa) typically are centered on docetaxel-based chemotherapy but are limited by the effects of multi-drug resistance. Recent advances have illustrated a role of contactin-1 (CNTN-1) in tumor chemoresistance, while the function and mechanism of CNTN-1...

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Detalles Bibliográficos
Publicado en:Arch Med Sci
Autores principales: Chen, Binshen, Zhang, Yiming, Li, Chaoming, Xu, Peng, Gao, Yubo, Xu, Yawen
Formato: Artigo
Lenguaje:Inglês
Publicado: Termedia Publishing House 2020
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811318/
https://ncbi.nlm.nih.gov/pubmed/33488868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2020.92939
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