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The regulation of the ZBP1-NLRP3 inflammasome and its implications in pyroptosis, apoptosis, and necroptosis (PANoptosis)

ZBP1 has been characterized as a critical innate immune sensor of not only viral RNA products but also endogenous nucleic acid ligands. ZBP1 sensing of the Z-RNA produced during influenza virus infection induces cell death in the form of pyroptosis, apoptosis, and necroptosis (PANoptosis). PANoptosi...

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Vydáno v:Immunol Rev
Hlavní autoři: Zheng, Min, Kanneganti, Thirumala-Devi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811275/
https://ncbi.nlm.nih.gov/pubmed/32729116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12909
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