The baseline interferon signature predicts disease severity over the subsequent 5 years in systemic lupus erythematosus

OBJECTIVES: Type I interferons (IFNs) play an important role in the pathophysiology of systemic lupus erythematosus (SLE). While cross-sectional data suggest an association between IFN-induced gene expression and SLE disease activity, interest in this as a biomarker of flare has been tempered by a l...

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Publicat a:Arthritis Res Ther
Autors principals: Mai, Lloyd, Asaduzzaman, Arundip, Noamani, Babak, Fortin, Paul R., Gladman, Dafna D., Touma, Zahi, Urowitz, Murray B., Wither, Joan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811214/
https://ncbi.nlm.nih.gov/pubmed/33451338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02414-0
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