Crosstalk between the muscular estrogen receptor α and BDNF/TrkB signaling alleviates metabolic syndrome via 7,8-dihydroxyflavone in female mice

OBJECTIVE: 7,8-Dihydroxyflavone (7,8-DHF), a small molecular mimetic of brain-derived neurotrophic factor (BDNF), alleviates high-fat diet-induced obesity in female mice in a sex-specific manner by activating muscular tropomyosin-related kinase B (TrkB). However, the underlying molecular mechanism f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Metab
Prif Awduron: Zhao, Zhenlei, Xue, Fan, Gu, Yanpei, Han, Jianxin, Jia, Yingxian, Ye, Keqiang, Zhang, Ying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2020
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811170/
https://ncbi.nlm.nih.gov/pubmed/33352311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101149
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