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CROP: a CRISPR/Cas9 guide selection program based on mapping guide variants
The off-target effect, in which DNA cleavage was conducted outside the targeted region, is a major problem which limits the applications of CRISPR/Cas9 genome editing system. CRISPR Off-target Predictor (CROP) is standalone program developed to address this problem by predicting off-target propensit...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7811000/ https://ncbi.nlm.nih.gov/pubmed/33452424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81297-2 |
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