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Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer

Colorectal cancer (CRC) is the third most common cancer worldwide. Even if 5‐fluorouracil (5‐FU) is used as the first‐line chemotherapeutic drug, responsiveness is only 20‐30%. Acquired resistance to 5‐FU contributes to both poor patient prognosis and relapse, emphasizing the need to identify biomar...

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Библиографические подробности
Опубликовано в: :J Cell Mol Med
Главные авторы: Blondy, Sabrina, Talbot, Hugo, Saada, Sofiane, Christou, Niki, Battu, Serge, Pannequin, Julie, Jauberteau, Marie‐Odile, Lalloué, Fabrice, Verdier, Mireille, Mathonnet, Muriel, Perraud, Aurélie
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810928/
https://ncbi.nlm.nih.gov/pubmed/33325631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15752
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