Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer

Colorectal cancer (CRC) is the third most common cancer worldwide. Even if 5‐fluorouracil (5‐FU) is used as the first‐line chemotherapeutic drug, responsiveness is only 20‐30%. Acquired resistance to 5‐FU contributes to both poor patient prognosis and relapse, emphasizing the need to identify biomar...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Blondy, Sabrina, Talbot, Hugo, Saada, Sofiane, Christou, Niki, Battu, Serge, Pannequin, Julie, Jauberteau, Marie‐Odile, Lalloué, Fabrice, Verdier, Mireille, Mathonnet, Muriel, Perraud, Aurélie
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810928/
https://ncbi.nlm.nih.gov/pubmed/33325631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15752
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