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A quantitative model of cellular decision making in direct neuronal reprogramming

The direct reprogramming of adult skin fibroblasts to neurons is thought to be controlled by a small set of interacting gene regulators. Here, we investigate how the interaction dynamics between these regulating factors coordinate cellular decision making in direct neuronal reprogramming. We put for...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Merlevede, Adriaan, Legault, Emilie M., Drugge, Viktor, Barker, Roger A., Drouin-Ouellet, Janelle, Olariu, Victor
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810861/
https://ncbi.nlm.nih.gov/pubmed/33452356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81089-8
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