Učitavanje...
CD14+ monocytes repress gamma globin expression at early stages of erythropoiesis
In β-hemoglobinopathies, reactivation of gamma- at the expense of beta-globin is a prominent therapeutic option. Expression of the globin genes is not strictly intrinsically regulated during erythropoiesis, supported by the observation that fetal erythroid cells switch to adult hemoglobin expression...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7810836/ https://ncbi.nlm.nih.gov/pubmed/33452379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81060-7 |
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