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Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo

Recently, studies about RNA modification dynamics in human RNAs are among the most controversially discussed. As a main reason, we identified the unavailability of a technique which allows the investigation of the temporal processing of RNA transcripts. Here, we present nucleic acid isotope labeling...

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Publicat a:Nat Commun
Autors principals: Heiss, Matthias, Hagelskamp, Felix, Marchand, Virginie, Motorin, Yuri, Kellner, Stefanie
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810713/
https://ncbi.nlm.nih.gov/pubmed/33452242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20576-4
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