Dopamine Transporter Localization in Medial Forebrain Bundle Axons Indicates Its Long-Range Transport Primarily by Membrane Diffusion with a Limited Contribution of Vesicular Traffic on Retromer-Positive Compartments

Dopamine transporter (DAT) controls dopamine neurotransmission by clearing synaptically released dopamine. However, trafficking itineraries of DAT, which determine its cell-surface concentration near synapses, are poorly characterized. It is especially unknown how DAT is transported between spatiall...

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Publicat a:J Neurosci
Autors principals: Bagalkot, Tarique R., Block, Ethan R., Bucchin, Kristen, Balcita-Pedicino, Judith Joyce, Calderon, Michael, Sesack, Susan R., Sorkin, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810657/
https://ncbi.nlm.nih.gov/pubmed/33234607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0744-20.2020
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