Inhibition of PD-1 Protects against TNBS-Induced Colitis via Alteration of Enteric Microbiota

METHODS: Colitis was induced in mice using 2,4,6-trinitrobenzene-sulfonic acid (TNBS), and mice were subsequently treated with either a PD-1 inhibitor or 5-amino-salicylic acid (ASA) as a positive control. Body weight, disease activity index (DAI), colon length, and tissue damage were evaluated, and...

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Bibliografski detalji
Izdano u:Biomed Res Int
Glavni autori: Xu, Hao-ming, Zhou, You-lian, Xu, Jing, Li, Ying-fei, Zhao, Chong, Huang, Hong-li, Du, Yan-lei, He, Jie, Zhou, Yong-jian, Nie, Yu-qiang
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2021
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810563/
https://ncbi.nlm.nih.gov/pubmed/33506015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/4192451
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