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Single-cell cytometry via multiplexed fluorescence prediction by label-free reflectance microscopy

Traditional imaging cytometry uses fluorescence markers to identify specific structures but is limited in throughput by the labeling process. We develop a label-free technique that alleviates the physical staining and provides multiplexed readouts via a deep learning–augmented digital labeling metho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Adv
Hauptverfasser: Cheng, Shiyi, Fu, Sipei, Kim, Yumi Mun, Song, Weiye, Li, Yunzhe, Xue, Yujia, Yi, Ji, Tian, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810377/
https://ncbi.nlm.nih.gov/pubmed/33523908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe0431
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