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Voxelotor: A Hemoglobin S Polymerization Inhibitor for the Treatment of Sickle Cell Disease
Sickle cell disease (SCD) affects millions of people throughout the world. Hemoglobin S (HbS) polymerization is the fundamental cause of SCD pathophysiology, which leads to hemolysis, increased viscosity, and acute vaso-occlusive episodes. Novel agents have been developed to target the pathophysiolo...
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| Pubblicato in: | J Adv Pract Oncol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Harborside Press LLC
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7810265/ https://ncbi.nlm.nih.gov/pubmed/33489427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6004/jadpro.2020.11.8.7 |
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