ACE2 expression is related to the interferon response in airway epithelial cells but is that functional for SARS-CoV-2 entry?

In vitro interferon (IFN)α treatment of primary human upper airway basal cells has been shown to drive ACE2 expression, the receptor of SARS-CoV-2. The protease furin is also involved in mediating SARS‐CoV‐2 and other viral infections, although its association with early IFN response has not been ev...

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Foilsithe in:Cytokine
Main Authors: Scagnolari, Carolina, Bitossi, Camilla, Viscido, Agnese, Frasca, Federica, Oliveto, Giuseppe, Scordio, Mirko, Petrarca, Laura, Mancino, Enrica, Nenna, Raffaella, Riva, Elisabetta, De Vito, Corrado, Midulla, Fabio, Antonelli, Guido, Pierangeli, Alessandra
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier Ltd. 2021
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810030/
https://ncbi.nlm.nih.gov/pubmed/33508651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2021.155430
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