Genipin and insulin combined treatment improves implant osseointegration in type 2 diabetic rats

BACKGROUND: Type 2 diabetes mellitus (T2DM) has a harmful effect on the stability and osseointegration of dental implants. T2DM induces mitochondrial damage by inhibiting AMPK signaling, resulting in oxidative stress and poor osteogenesis in the peri-implant bone area. Genipin is a major component o...

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Bibliografiske detaljer
Udgivet i:J Orthop Surg Res
Main Authors: Zhang, Jiajia, Wang, Ya-nan, Jia, Tingting, Huang, Haiyun, Zhang, Dongjiao, Xu, Xin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809857/
https://ncbi.nlm.nih.gov/pubmed/33446235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-021-02210-1
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