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Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function

TLR4 location, and bacterial species-derived lipopolysaccharides, play a significant role in the downstream activation of transcription factors, accessory molecules, and products. Here, this is demonstrated through the use of classically-activated and alternatively-activated macrophages. We show tha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Stephens, Matthew, Liao, Shan, von der Weid, Pierre-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809447/
https://ncbi.nlm.nih.gov/pubmed/33446670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79145-w
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