Decreased levels of circulating cytokines VEGF, TNF-β and IL-15 indicate PD-L1 overexpression in tumours of primary breast cancer patients

Programmed death ligand 1 (PD-L1) overexpression has been associated with poor clinical outcomes in several human cancers whose increased malignant behaviour might be related to PD-L1 mediated systemic immunological tolerance. This study aims to verify if circulating cytokines may serve as a proxy f...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Cierna, Zuzana, Smolkova, Bozena, Cholujova, Dana, Gronesova, Paulina, Miklikova, Svetlana, Cihova, Marina, Plava, Jana, Mego, Michal
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809365/
https://ncbi.nlm.nih.gov/pubmed/33446741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80351-9
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