Late p65 nuclear translocation in glioblastoma cells indicates non-canonical TLR4 signaling and activation of DNA repair genes

Glioblastoma (GBM) is the most aggressive brain primary malignancy. Toll-like receptor 4 (TLR4) has a dual role in cell fate, promoting cell survival or death depending on the context. Here, we analyzed TLR4 expression in different grades of astrocytoma, and observed increased expression in tumors,...

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Foilsithe in:Sci Rep
Main Authors: Moretti, Isabele F., Lerario, Antonio M., Trombetta-Lima, Marina, Sola, Paula R., da Silva Soares, Roseli, Oba-Shinjo, Sueli M., Marie, Suely K. N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809124/
https://ncbi.nlm.nih.gov/pubmed/33446690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79356-1
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