Reestablishment of Redox Homeostasis in the Nociceptive Primary Afferent as a Mechanism of Antinociception Promoted by Mesenchymal Stem/Stromal Cells in Oxaliplatin-Induced Chronic Peripheral Neuropathy

Painful neuropathy is a common adverse effect of oxaliplatin (OXL), a platinum-derivative chemotherapeutic agent. Oxidative stress and mitochondrial dysfunction are key factors contributing to the development of OXL-induced peripheral neuropathy (OIPN). Based on the antioxidant and antinociceptive p...

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Vydáno v:Stem Cells Int
Hlavní autoři: Oliveira, Anna Lethicia L., Santos, Gisele G. L., Espirito-Santo, Renan F., Silva, Gessica Sabrina A., Evangelista, Afrânio F., Silva, Daniela N., Soares, Milena B. P., Villarreal, Cristiane Flora
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808808/
https://ncbi.nlm.nih.gov/pubmed/33505472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8815206
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