Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily

Sec14, the major yeast phosphatidylinositol (PtdIns)/phosphatidylcholine (PtdCho) transfer protein, regulates essential interfaces between lipid metabolism and membrane trafficking from the trans-Golgi network (TGN). How Sec14 does so remains unclear. We report that Sec14 binds PtdIns and PtdCho at...

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Publicat a:Mol Cell
Autors principals: Schaaf, Gabriel, Ortlund, Eric A., Tyeryar, Kimberly R., Mousley, Carl J., Ile, Kristina E., Garrett, Teresa A., Ren, Jihui, Woolls, Melissa J., Raetz, Christian R.H., Redinbo, Matthew R., Bankaitis, Vytas A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808562/
https://ncbi.nlm.nih.gov/pubmed/18243114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.11.026
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