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Exploring Excitotoxicity and Regulation of a Constitutively Active TRP Ca(2+) Channel in Drosophila

Unregulated Ca(2+) influx affects intracellular Ca(2+) homoeostasis, which may lead to neuronal death. In Drosophila, following the activation of rhodopsin the TRP Ca(2+) channel is open to mediate the light-dependent depolarization. A constitutively active TRP channel triggers the degeneration of T...

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Detalhes bibliográficos
Publicado no:Fly (Austin)
Main Authors: Shieh, Bih-Hwa, Nuzum, Lucinda, Kristaponyte, Inga
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808436/
https://ncbi.nlm.nih.gov/pubmed/33200658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336934.2020.1851586
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