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Current cancer driver variant predictors learn to recognize driver genes instead of functional variants

BACKGROUND: Identifying variants that drive tumor progression (driver variants) and distinguishing these from variants that are a byproduct of the uncontrolled cell growth in cancer (passenger variants) is a crucial step for understanding tumorigenesis and precision oncology. Various bioinformatics...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Raimondi, Daniele, Passemiers, Antoine, Fariselli, Piero, Moreau, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807764/
https://ncbi.nlm.nih.gov/pubmed/33441128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00930-0
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