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Depressive effectiveness of vigabatrin (γ-vinyl-GABA), an antiepileptic drug, in intermediate-conductance calcium-activated potassium channels in human glioma cells

BACKGROUND: Vigabatrin (VGB) is an approved non-traditional antiepileptic drug that has been revealed to have potential for treating brain tumors; however, its effect on ionic channels in glioma cells remains largely unclear. METHODS: With the aid of patch-clamp technology, we investigated the effec...

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Publicat a:BMC Pharmacol Toxicol
Autors principals: Hung, Te-Yu, Huang, Huai-Ying Ingrid, Wu, Sheng-Nan, Huang, Chin-Wei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807716/
https://ncbi.nlm.nih.gov/pubmed/33441172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-021-00472-3
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