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The NADase enzyme CD38: an emerging pharmacological target for Systemic Sclerosis, Systemic Lupus Erythematosus and Rheumatoid Arthritis.
PURPOSE OF REVIEW: Here we review recent literature on the emerging role of nicotinamide adenine dinucleotide (NAD(+)) metabolism and its dysfunction via the enzyme CD38 in the pathogenesis of rheumatologic diseases. We evaluate the potential of targeting CD38 to ameliorate NAD(+)-related metabolic...
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| Publicado en: | Curr Opin Rheumatol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7807656/ https://ncbi.nlm.nih.gov/pubmed/32941246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOR.0000000000000737 |
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