Understanding ER+ Breast Cancer Dormancy using Bioinspired Synthetic Matrices for Long-term 3D Culture and Insights into Late Recurrence

Late recurrences of breast cancer are hypothesized to originate from disseminated tumor cells that re-activate after a long period of dormancy, ≥ 5 years for estrogen-receptor positive (ER+) tumors. An outstanding question remains as to what the key microenvironment interactions are that regulate th...

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Vydáno v:Adv Biosyst
Hlavní autoři: Ovadia, Elisa M., Pradhan, Lina, Sawicki, Lisa A., Cowart, Julie, Huber, Rebecca E., Polson, Shawn W., Chen, Chuming, van Golen, Kenneth L., Ross, Karen E., Wu, Cathy, Kloxin, April M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807552/
https://ncbi.nlm.nih.gov/pubmed/32603024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.202000119
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