Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status

IMPORTANCE: Combining information on polygenic risk scores (PRSs) with other known risk factors could potentially improve the identification of risk of depression in the general population. However, to our knowledge, no study has estimated the association of PRS with the absolute risk of depression,...

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Vydáno v:JAMA Psychiatry
Hlavní autoři: Agerbo, Esben, Trabjerg, Betina B., Børglum, Anders D., Schork, Andrew J., Vilhjálmsson, Bjarni J., Pedersen, Carsten B., Hakulinen, Christian, Albiñana, Clara, Hougaard, David M., Grove, Jakob, McGrath, John J., Bybjerg-Grauholm, Jonas, Mors, Ole, Plana-Ripoll, Oleguer, Werge, Thomas, Wray, Naomi R., Mortensen, Preben Bo, Musliner, Katherine L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2021
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807393/
https://ncbi.nlm.nih.gov/pubmed/33439215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2020.4172
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