Effect of Bimagrumab vs Placebo on Body Fat Mass Among Adults With Type 2 Diabetes and Obesity: A Phase 2 Randomized Clinical Trial

IMPORTANCE: Antibody blockade of activin type II receptor (ActRII) signaling stimulates skeletal muscle growth. Previous clinical studies suggest that ActRII inhibition with the monoclonal antibody bimagrumab also promotes excess adipose tissue loss and improves insulin resistance. OBJECTIVE: To eva...

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Detaylı Bibliyografya
Yayımlandı:JAMA Netw Open
Asıl Yazarlar: Heymsfield, Steven B., Coleman, Laura A., Miller, Ram, Rooks, Daniel S., Laurent, Didier, Petricoul, Olivier, Praestgaard, Jens, Swan, Therese, Wade, Thomas, Perry, Robert G., Goodpaster, Bret H., Roubenoff, Ronenn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Medical Association 2021
Konular:
Original Investigation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807292/
https://ncbi.nlm.nih.gov/pubmed/33439265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2020.33457
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