Effect of Bimagrumab vs Placebo on Body Fat Mass Among Adults With Type 2 Diabetes and Obesity: A Phase 2 Randomized Clinical Trial

IMPORTANCE: Antibody blockade of activin type II receptor (ActRII) signaling stimulates skeletal muscle growth. Previous clinical studies suggest that ActRII inhibition with the monoclonal antibody bimagrumab also promotes excess adipose tissue loss and improves insulin resistance. OBJECTIVE: To eva...

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Bibliografiska uppgifter
I publikationen:JAMA Netw Open
Huvudupphovsmän: Heymsfield, Steven B., Coleman, Laura A., Miller, Ram, Rooks, Daniel S., Laurent, Didier, Petricoul, Olivier, Praestgaard, Jens, Swan, Therese, Wade, Thomas, Perry, Robert G., Goodpaster, Bret H., Roubenoff, Ronenn
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Medical Association 2021
Ämnen:
Original Investigation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807292/
https://ncbi.nlm.nih.gov/pubmed/33439265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2020.33457
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