Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)

Chimpanzees are genetically and physiologically similar to humans. Several pharmacokinetic models of propofol are available and target controlled infusion (TCI) of propofol is established in humans, but not in chimpanzees. The purpose of this study was to investigate if human pharmacokinetic models...

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Publicado en:Sci Rep
Main Authors: Miyabe-Nishiwaki, T., Kaneko, A., Yamanaka, A., Maeda, N., Suzuki, J., Tomonaga, M., Matsuzawa, T., Muta, K., Nishimura, R., Yajima, I., Eleveld, D. J., Absalom, A. R., Masui, K.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806914/
https://ncbi.nlm.nih.gov/pubmed/33441704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79914-7
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