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Differential organ-specific inflammatory response to progranulin in high-fat diet-fed mice

Progranulin (PGRN) has been reported to bind tumor necrosis factor (TNF) receptor and to inhibit TNFα signaling. We evaluated the effect of augmentation of TNFα signaling by PGRN deficiency on the progression of kidney injury. Eight-week-old PGRN knockout (KO) and wild-type (WT) mice were fed a stan...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Murakoshi, Maki, Gohda, Tomohito, Adachi, Eri, Ichikawa, Saki, Hagiwara, Shinji, Suzuki, Yusuke
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806827/
https://ncbi.nlm.nih.gov/pubmed/33441916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80940-8
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