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Adenosine A2A receptor signaling promotes FoxO associated autophagy in chondrocytes
Autophagy, a homeostatic pathway upregulated during cellular stress, is decreased in osteoarthritic chondrocytes and this reduction in autophagy is thought to contribute to the development and progression of osteoarthritis (OA). The adenosine A2A receptor (A2AR) is a potent anti-inflammatory recepto...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7806643/ https://ncbi.nlm.nih.gov/pubmed/33441836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80244-x |
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