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Dysregulation of sonic hedgehog signaling causes hearing loss in ciliopathy mouse models
Defective primary cilia cause a range of diseases known as ciliopathies, including hearing loss. The etiology of hearing loss in ciliopathies, however, remains unclear. We analyzed cochleae from three ciliopathy mouse models exhibiting different ciliogenesis defects: Intraflagellar transport 88 (Ift...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7806262/ https://ncbi.nlm.nih.gov/pubmed/33382037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56551 |
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