A Positive Feedback Loop Between TGFβ and Androgen Receptor Supports Triple-negative Breast Cancer Anoikis Resistance

Triple-negative breast cancer (TNBC) is an aggressive subtype with peak recurrence as metastatic disease within the first few years of diagnosis. Androgen receptor (AR) expression is increased in anchorage-independent cells in TNBC preclinical models. Both AR knockdown and inhibition lead to reduced...

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Vydáno v:Endocrinology
Hlavní autoři: Rosas, Emmanuel, Roberts, Justin T, O’Neill, Kathleen I, Christenson, Jessica L, Williams, Michelle M, Hanamura, Toru, Spoelstra, Nicole S, Vahrenkamp, Jeffery M, Gertz, Jason, Richer, Jennifer K
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806239/
https://ncbi.nlm.nih.gov/pubmed/33294922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa226
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