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Treg-recruiting microspheres prevent inflammation in a murine model of dry eye disease

Dry eye disease (DED) is a common ocular disorder affecting millions of individuals worldwide. The pathology of DED involves the infiltration of CD4(+) lymphocytes, leading to tear film instability and destructive inflammation. In the healthy steady state, a population of immunosuppressive T-cells c...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Ratay, Michelle L., Glowacki, Andrew J., Balmert, Stephen C., Acharya, Abhinav P., Polat, Julia, Andrews, Lawrence P., Fedorchak, Morgan V., Schuman, Joel S., Vignali, Dario A.A., Little, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805562/
https://ncbi.nlm.nih.gov/pubmed/28501670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.05.007
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