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Quantitative Approaches for Scoring in vivo Neuronal Aggregate and Organelle Extrusion in Large Exopher Vesicles in C. elegans

Toxicity of misfolded proteins and mitochondrial dysfunction are pivotal factors that promote age-associated functional neuronal decline and neurodegenerative disease across species. Although these neurotoxic challenges have long been considered to be cell-intrinsic, considerable evidence now suppor...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Arnold, Meghan Lee, Cooper, Jason, Grant, Barth D., Driscoll, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805482/
https://ncbi.nlm.nih.gov/pubmed/33016946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/61368
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