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Crystallographic molecular replacement using an in silico-generated search model of SARS-CoV-2 ORF8

The majority of crystal structures are determined by the method of molecular replacement (MR). The range of application of MR is limited mainly by the need for an accurate search model. In most cases, pre-existing experimentally determined structures are used as search models. In favorable cases, ab...

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Bibliographic Details
Published in:bioRxiv
Main Authors: Flower, Thomas G., Hurley, James H.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805452/
https://ncbi.nlm.nih.gov/pubmed/33442695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.05.425441
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