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Fibrinolysis influences SARS-CoV-2 infection in ciliated cells

Rapid spread of COVID-19 has caused an unprecedented pandemic worldwide, and an inserted furin site in SARS-CoV-2 spike protein (S) may account for increased transmissibility. Plasmin, and other host proteases, may cleave the furin site of SARS-CoV-2 S protein and γ subunits of epithelial sodium cha...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Hou, Yapeng, Ding, Yan, Nie, Hongguang, Ji, Hong-Long
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805445/
https://ncbi.nlm.nih.gov/pubmed/33442688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.07.425801
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