Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

BACKGROUND: The SARS-CoV-2 pandemic is currently leading to increasing numbers of COVID-19 patients all over the world. Clinical presentations range from asymptomatic, mild respiratory tract infection, to severe cases with acute respiratory distress syndrome, respiratory failure, and death. Reports...

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Publicat a:Genome Med
Autors principals: Aschenbrenner, Anna C., Mouktaroudi, Maria, Krämer, Benjamin, Oestreich, Marie, Antonakos, Nikolaos, Nuesch-Germano, Melanie, Gkizeli, Konstantina, Bonaguro, Lorenzo, Reusch, Nico, Baßler, Kevin, Saridaki, Maria, Knoll, Rainer, Pecht, Tal, Kapellos, Theodore S., Doulou, Sarandia, Kröger, Charlotte, Herbert, Miriam, Holsten, Lisa, Horne, Arik, Gemünd, Ioanna D., Rovina, Nikoletta, Agrawal, Shobhit, Dahm, Kilian, van Uelft, Martina, Drews, Anna, Lenkeit, Lena, Bruse, Niklas, Gerretsen, Jelle, Gierlich, Jannik, Becker, Matthias, Händler, Kristian, Kraut, Michael, Theis, Heidi, Mengiste, Simachew, De Domenico, Elena, Schulte-Schrepping, Jonas, Seep, Lea, Raabe, Jan, Hoffmeister, Christoph, ToVinh, Michael, Keitel, Verena, Rieke, Gereon, Talevi, Valentina, Skowasch, Dirk, Aziz, N. Ahmad, Pickkers, Peter, van de Veerdonk, Frank L., Netea, Mihai G., Schultze, Joachim L., Kox, Matthijs, Breteler, Monique M. B., Nattermann, Jacob, Koutsoukou, Antonia, Giamarellos-Bourboulis, Evangelos J., Ulas, Thomas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805430/
https://ncbi.nlm.nih.gov/pubmed/33441124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00823-5
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