Truncation of 3′ CCND1 by t(11;22) leads to negative SP4 CCND1 immunohistochemistry in blastoid mantle cell lymphoma

t(11;22)(q13;q11)/CCND1-IGL resulted in truncation of the CCND1 3′ coding sequences in a case of blastoid variant mantle cell lymphoma. The translocation generated CCND1 with a C-terminal alteration, leading to negative CCND1 immunohistochemistry by SP4 monoclonal antibody.

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Vydáno v:Blood Adv
Hlavní autoři: Maekawa, Fumiyo, Kishimori, Chiyuki, Nakagawa, Miho, Takeoka, Kayo, Fukutsuka, Katsuhiro, Hayashida, Masahiko, Iioka, Futoshi, Fujimoto, Masakazu, Takeuchi, Kengo, Nakamine, Hirokazu, Ohno, Hitoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2021
Témata:
Exceptional Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805338/
https://ncbi.nlm.nih.gov/pubmed/33570637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003417
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