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Pre-HCT mosaicism increases relapse risk and lowers survival in acute lymphoblastic leukemia patients post–unrelated HCT

Pre-HCT mosaicism is related to increased relapse risk and lower survival after unrelated HCT, independent of cytogenetics at diagnosis. Pre-HCT mosaicism could be a useful clinical tool to guide risk stratification in acute lymphoblastic leukemia patients.

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Bibliografski detalji
Izdano u:Blood Adv
Glavni autori: Wang, Yiwen, Zhou, Weiyin, Wang, Junke, Karaesmen, Ezgi, Tang, Hancong, McCarthy, Philip L., Pasquini, Marcelo C., Wang, Youjin, McReynolds, Lisa J., Katki, Hormuzd A., Machiela, Mitchell J., Yeager, Meredith, Pooler, Loreall, Sheng, Xin, Haiman, Christopher A., Van Den Berg, David, Spellman, Stephen R., Wang, Tao, Kuxhausen, Michelle, Chanock, Stephen J., Lee, Stephanie J., Clay-Gilmour, Alyssa I., Hahn, Theresa E., Gadalla, Shahinaz M., Sucheston-Campbell, Lara E.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805319/
https://ncbi.nlm.nih.gov/pubmed/33570634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003366
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