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Overcoming resistance to targeted therapies in chronic lymphocytic leukemia

Insight into the critical role of B-cell receptor signaling for the pathogenesis of chronic lymphocytic leukemia (CLL) led to the development of targeted therapies directed at key regulators of cell survival. Agents targeting B-cell lymphoma-2 protein, Bruton’s tyrosine kinase (BTK), and phosphatidy...

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Skånland, Sigrid S., Mato, Anthony R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805313/
https://ncbi.nlm.nih.gov/pubmed/33570649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003423
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