Structure and compositional analysis of aluminum oxyhydroxide adsorbed pertussis vaccine

PURPOSE: The goal of this study was to characterize an acellular pertussis vaccine (Tdap) containing genetically modified pertussis toxin (gdPT) and TLR agonist adsorbed to AlOOH adjuvant. METHODS: Several analytical tools including nanoDSF, FTIR, and LD were used to examine the conformation of nove...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Duprez, Jessica, Kalbfleisch, Kristen, Deshmukh, Sasmit, Payne, Jessie, Haer, Manjit, Williams, Wayne, Durowoju, Ibrahim, Kirkitadze, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804342/
https://ncbi.nlm.nih.gov/pubmed/33489011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.12.023
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