Impact of low-frequency coding variants on human facial shape

The contribution of low-frequency variants to the genetic architecture of normal-range facial traits is unknown. We studied the influence of low-frequency coding variants (MAF < 1%) in 8091 genes on multi-dimensional facial shape phenotypes in a European cohort of 2329 healthy individuals. Using...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Dongjing, Alhazmi, Nora, Matthews, Harold, Lee, Myoung Keun, Li, Jiarui, Hecht, Jacqueline T., Wehby, George L., Moreno, Lina M., Heike, Carrie L., Roosenboom, Jasmien, Feingold, Eleanor, Marazita, Mary L., Claes, Peter, Liao, Eric C., Weinberg, Seth M., Shaffer, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804299/
https://ncbi.nlm.nih.gov/pubmed/33436952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80661-y
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