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Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii

Acinetobacter baumannii is a highly antibiotic resistant Gram-negative bacterium that causes life-threatening infections in humans with a very high mortality rate. A. baumannii is an extracellular pathogen with poorly understood virulence mechanisms. Here we report that A. baumannii employs the rele...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Tiku, Varnesh, Kofoed, Eric M., Yan, Donghong, Kang, Jing, Xu, Min, Reichelt, Mike, Dikic, Ivan, Tan, Man-Wah
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804284/
https://ncbi.nlm.nih.gov/pubmed/33436835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79966-9
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