Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis

Nonribosomal peptide synthetases containing starter condensation domains direct the biosynthesis of nonribosomal lipopeptides, which generally exhibit wide bioactivities. The acyl chain has strong impacts on bioactivity and toxicity, but the lack of an in-depth understanding of starter condensation...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhong, Lin, Diao, Xiaotong, Zhang, Na, Li, Fengwei, Zhou, Haibo, Chen, Hanna, Bai, Xianping, Ren, Xintong, Zhang, Youming, Wu, Dalei, Bian, Xiaoying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804268/
https://ncbi.nlm.nih.gov/pubmed/33436600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20548-8
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