Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis

Nonribosomal peptide synthetases containing starter condensation domains direct the biosynthesis of nonribosomal lipopeptides, which generally exhibit wide bioactivities. The acyl chain has strong impacts on bioactivity and toxicity, but the lack of an in-depth understanding of starter condensation...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Zhong, Lin, Diao, Xiaotong, Zhang, Na, Li, Fengwei, Zhou, Haibo, Chen, Hanna, Bai, Xianping, Ren, Xintong, Zhang, Youming, Wu, Dalei, Bian, Xiaoying
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804268/
https://ncbi.nlm.nih.gov/pubmed/33436600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20548-8
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